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DSIP
SleepSingleAlso known as: Delta Sleep-Inducing Peptide
A neuropeptide first isolated from rabbit cerebral venous blood, studied for sleep regulation, stress modulation, and pain modulation.
Half-life
0.1 h
Common dose
100 – 300 mcg
Dosing frequency
Daily
Administration
Subcutaneous, Intranasal
How it works
DSIP is theorized to modulate hypothalamic sleep-regulating circuits and influence the HPA axis, though the precise mechanism remains incompletely characterized.
Protocol notes
Subcutaneous protocols use 100–300 mcg 30–60 minutes before bed. Cycles of 2–4 weeks with breaks. Intranasal use is less common.
Reported side effects
Generally well-tolerated. Possible morning grogginess, vivid dreams, mild headache.